CBD Nano-encapsulation: What is Nano CBD?

CBD Drinks from Upstate Elevator

If you have been struggling to keep up with the many new developments emerging in the hemp industry, you’re not alone — especially if you have been hearing about nano-encapsulated CBD and CBG technology. Even if you consider yourself familiar with more than the basics when it comes to extraction methods, this term may be the one that throws you for a loop. It begs you to ask: how many ways can you get CBD out of a hemp plant? Rather than an extraction method, nano-encapsulation is a technology applied to your chosen extract. There are many different ways to extract CBD, the “right” one all depends on what you value and prioritize about the process and its resulting product. So, what’s the deal with CBD nanotechnology and nano CBD?


What Is CBD Nano-encapsulation?

Although nano-encapsulation can be used to enhance a consumer’s CBD experience, it’s not exclusive to extracting cannabinoids from hemp. In general, it is the coating of one substance on another material at a molecular scale. It deals with extremely small particles, anywhere from 1 to 999 nanometers. CBD nanotechnology applies a process that breaks the cannabinoid down into teeny, tiny nanoparticles, and wraps them in a substance that is easier for the body to absorb.

The Upstate Advantage: Particle Size

At Upstate Elevator, we achieve an average particle size of about 70 nanometers (for context, a red blood cell is about 80,000 nanometers), which is very small. We validate this with third party testing through dynamic light scattering & laser diffraction, so we’re confident you are getting the best product we can craft.

Why Use Nano CBD?

CBD is often referred to as a hydrophobic molecule because it is not water soluble and doesn’t bind with water molecules. Because the cannabinoid can’t naturally be dissolved in water, it requires a particular process in order to be infused into a liquid like water or any other beverage. That’s where CBD nanoencapsulation comes in. Through an ultrasonic processing method, it encapsulates the CBD inside a tiny structure, called either a liposome or a micelle. The process emulsifies the cannabinoid, allowing it to be equally distributed throughout a liquid. Typically, products that use “nano CBD” in their formulation do so either to increase the bioavailability or for it’s water-soluble properties.

The Upstate Advantage: Micelle vs. Liposome

At Upstate, we use micellar structures to trap the CBD inside of tiny structures called micelles. While both micelles and liposomes provide the advantage of making hard-to-absorb substances easier to assimilate, micelles have been scientifically validated to be more effective and are the preferred form for the pharmaceutical industry.

Relative size and composition of a Micelle (left) versus a Liposome (right)

The Benefits of Nano CBD

A primary benefit of nano CBD is the increase in bioavailability. Bioavailability refers to how efficiently your body can absorb a substance—how much of it, and how quickly it gets into your bloodstream. This means that more of what you’ve purchased actually gets absorbed. Nano-encapsulated micellar structures are 50% to 90% more bioavailable than the same unmodified compound.

A primary benefit of nano CBD is the increase in bioavailability. Bioavailability refers to how efficiently your body can absorb a substance—how much of it, and how quickly it gets into your bloodstream.

Another big advantage is the speed with which nano CBD starts working. Because it is composed of very small particles, it can bypass your liver and be absorbed directly into your bloodstream.

By reducing the size of the particles, we increase the total surface area of CBD in contact with tissue, helping to speed absorption. These nano CBD particles can enter into different types of tissues that normal particle sizes are not able to pass through. With a nano beverage, the CBD starts absorbing as soon as it touches your lips and works faster than traditional products
Due to these advantages, nano encapsulated substances are considered up to 6 times more powerful. So, you may not need as high a dose as you would with traditional products that aren’t using micelle nanotechnology.

Where to Find Quality Nano CBD Products

Our proprietary method is very similar to the technique that pharmaceutical companies use. We achieve average particle sizes of about 70 nanometers, not only to enhance potency and stability, but to reach maximum absorption. All of our infused beverages use nano CBD allowing your body to absorb CBD up to six times faster. There are four different flavors to choose from — our African Ginger & Mexican Lime Soda sweetened with agave and the unsweetened, zero-calorie Raspberry Hibiscus Lime or Black Cherry Lemon Seltzers, and our newest, multi-cannabinoid CBG+CBD Wild Strawberry Tangerine seltzer. Get your nano on with Upstate today!